MRS

Spectroscopy

About Group

The first studies were performed on whole-body tomographs with a magnetic field of 1.5T. The group currently has a 3T VIDA tomograph available. Some studies are combined with the use of a 1.5T Avanto-fit tomograph and possibly a 7T Magnetom tomograph in collaboration with the Vienna Medical University. 

Traditionally, the most important area of ​​¹H spectroscopy is ¹H MR spectroscopy of the brain. Extensive control data sets and special software developed in the workplace are available for this area of ​​research. This area of ​​research and clinical applications is currently being implemented in cooperation with the radiology department of the Motol University Hospital. 

Although the working group also has experience with kidney and prostate examinations, the main focus is currently on the study and use of MR spectroscopy and MR imaging of the liver and muscles in connection with IKEM’s clinical focus. ¹H MR spectroscopy focuses on determining hepatic steatosis in patients with various liver diseases, before and after liver transplantation and in relation to dietary interventions. Steatosis is determined using both our spectroscopic techniques and the MR-LiverLab technique from Siemens. Special procedures have been developed for the analysis of liver fatty acid spectra (metabolic profile) or muscle spectra (MEGA PRESS techniques). 

Studies in ³¹P MR spectroscopy focus on the research and use of dynamic ³¹P MR calf muscle spectroscopy. Based on many years of experience, a computer-controlled MR compatible ergometer was designed for this purpose. At the same time, the method of processing and archiving dynamic MR spectra has improved. We focus primarily on the area of ​​IKEM patients with various muscle diseases.